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Diagnostic Criteria for Relapsing Polychondritis

Three or more clinical signs must be present:

  1. Recurrent chondritis both auricles
  2. Non-erosive inflammatory polyarthritis
  3. Nasal chondritis
  4. Ocular inflammation
  5. Respiratory tract chondritis
  6. Cochlear and, or, vestibular dysfunction

OR 1 or more signs with histologic confirmation

OR Chondritis in 2 or more separate sites AND response to steroids or immunosuppression

Differential diagnosis for these individual symptoms and signs includes most of the autoimmune disorders and other infectious and non-infectious granulomatous disorders including Wegener's granulomatosis, polyarteritis nodosa (PAN), Takayasu's arteritis, giant cell arteritis (GCA), rheumatoid arthritis, Reiter's syndrome, rheumatic fever, polymorphic reticulosis, syphilis, tuberculosis, histoplasmosis, leprosy, sarcoidosis, and malignancy.

Related Criteria

Revised ARA Criteria for the Classification of Rheumatoid Arthritis (RA)

Classification Criteria for the Diagnosis of Systemic Lupus Erythematosus (SLE)

Criteria for the Classification of Systemic Sclerosis (Scleroderma)

ACR Criteria for the Classification of Polyarteritis Nodosa (PAN)

ACR Criteria for the Classification of Churg-Strauss Syndrome (CSS)

ACR Criteria for the Classification of Giant-Cell Arteritis

ACR Criteria for the Classification of Hypersensitivity Vasculitis

Revised International Classification Criteria for Sjögren's Syndrome (SS)

1990 Criteria of American College of Rheumatology for the Classification of Takayasu Arteritis

Classification Criteria for Osteoarthritis

Criteria for the Classification of Wegener's Granulomatosis (WG)

Diagnostic Criteria for Autoimmune Hepatitis (AIH)

Diagnostic Criteria for Kawasaki Disease

Names and definitions of vasculitis adopted by the Chapel Hill Consensus Conference

Diagnostic Criteria for Mixed Connective Tissue Disease (MCTD)

Criteria for the Classification of the Antiphospholipid Syndrome (APS)




  1. Gergely P Jr, Poor G. Relapsing polychondritis. Best Pract Res Clin Rheumatol. 2004 Oct;18(5):723-38. [Medline]

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Created: May 26, 2005
Last Modified: 10/23/2010

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