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Rochester Criteria for Identifying Febrile Infants at Low Risk for Serious Bacterial Infection

1- Infant appears generally well

2- Infant has been previously healthy:

  • Born at term (>/=37 weeks of gestation)

  • No perinatal antimicrobial therapy

  • No treatment for unexplained hyperbilirubinemia

  • No previous antimicrobial therapy

  • No previous hospitalization

  • No chronic or underlying illness

  • Not hospitalized longer than mother

3- Infant has no evidence of skin, soft tissue, bone, joint or ear infection

4- Infant has these laboratory values:

  • White blood cell count of 5,000 to 15,000 per mm3 (5 to 15 x 109 per L)

  • Absolute band cell count of </=1,500 per mm3 (</=1.5 x 109 per L)

  • Ten or fewer white blood cells per high-power field on microscopic examination of urine

  • Five or fewer white blood cells per high-power field on microscopic examination of stool in infant with diarrhea

Related Criteria

Definition and Causes of Apparent Life-Threatening Events (ALTE)

Causes of Bacteraemia and Meningitis in Young Children

Clinical and Laboratory "Low Risk" Criteria for Children Younger Than 3 Months with Fever and No Focus of Infection

Diagnostic Criteria for Cystic Fibrosis (CF)

Modified Bell´s Staging Criteria for Necrotizing Enterocolitis (NEC)



1.      Jaskiewicz JA, McCarthy CA, Richardson AC, White KC, Fisher DJ, Dagan R, Powell KR. Febrile infants at low risk for serious bacterial infection--an appraisal of the Rochester criteria and implications for management. Febrile Infant Collaborative Study Group. Pediatrics. 1994 Sep;94(3):390-6. [Medline]

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Created: July 21, 2005
Last Modified: 10/23/2010

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