Syndromes or Disease Entities That Have Been Associated with Polycystic Ovaries

·        Hyperandrogenism

o        Steroidogenic enzyme deficiencies

§         Congenital adrenal hyperplasia

§         Aromatase deficiency

o        Androgen-secreting tumors

§         Ovarian

§         Adrenal

o        Exogenous androgens

§         Anabolic steroids

§         Transsexual hormone replacement

o        Other

§         Acne

§         Idiopathic hirsutism

·        Hyperandrogenism and Insulin Resistance

o        Congenital

§         Type A syndrome

§         Type B syndrome

§         Leprechaunism

§         Lipoatrophic diabetes

§         Rabson-Mendenhall syndrome

§         Polycystic ovary syndrome

o        Acquired

§         Cushing's syndrome

·      Insulin Resistance

o        Glycogen storage diseases

o        Type 2 diabetes

·      Other

o        Central nervous system

§         Trauma/lesions

§         Hyperprolactinemia

o        Nonhormonal medications

§         Valproate

o        Heriditary angioedema

o        Bulimia

o        Idiopathic (includes normoandrogenic women with cyclic menses)


  1. The Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod. 2004 Jan;19(1):41-7. [Medline]
  2. Legro R. Diagnostic Criteria in Polycystic Ovary Syndrome. Semin Reprod Med. 2003 Aug;21(3):267-75 [Medline]
  3. Reaven G. The metabolic syndrome or the insulin resistance syndrome? Different names, different concepts, and different goals. Endocrinol Metab Clin North Am. 2004 Jun;33(2):283-303. [Medline]


Created: May 10, 2005
Last Modified: 02/28/2006