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Criteria for Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

  • Hypotonic hyponatremia

  • Urine osmolality >100 mOsm per kg (100 mmol per kg)

  • Absence of extracellular volume depletion

  • Normal thyroid and adrenal function

  • Normal cardiac, hepatic and renal function



  1. Fried LF, Palevsky PM. Hyponatremia and hypernatremia. Med Clin North Am 1997;81:585-609. [Medline]

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Created: Aug 09, 2008
Last Modified: 10/17/2010

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