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Cardiovascular Major Risk Factors

  • Hypertension
  • Cigarette smoking
  • Obesity (BMI >/=30): indicates body mass index calculated as weight in kilograms divided by the square of height in meters
  • Physical inactivity
  • Dyslipidemia
  • Diabetes mellitus
  • Microalbuminuria or estimated glomerular filtration rate (GFR) <60 mL/min
  • Age (>55 years for men, >65 years for women)
  • Family history of premature cardiovascular disease (men <55 years or women 65 years)

Related Criteria:

Criteria for Evaluating the Effectiveness of Screening for a Risk Factor

NYHA Functional Classification for Congestive Heart Failure

Framingham Criteria for Congestive Heart Failure

Duke Criteria for Infective Endocarditis (IE)

Revised Jones Criteria for Acute Rheumatic Fever (ARF)

Wells Clinical Prediction Rule for Pulmonary Embolism and Deep Venous Thrombosis

Braunwald Classification of Unstable Angina (UA)

Diagnostic Criteria for Thromboangiitis Obliterans (Buerger’s Disease)



  1. Chobaniam AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL, Jones DW, Materson BJ, Oparil S, Wright JT, Roccella EJ, and the National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. The JNC 7 Report. JAMA 2003;289:2560-2572 [Medline]

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Created: April 29, 2005
Last Modified: 10/17/2010

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