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Diagnostic Criteria for Thromboangiitis Obliterans (Buerger’s Disease)

Since specificity of Buerger’s disease is characterized by peripheral ischemia of an inflammatory nature and with a self-limiting course, diagnostic criteria should be discussed from clinical of view.

Several different criteria have been proposed for the diagnosis of thromboangiitis obliterans:

Diagnostic Criteria of Shionoya:

  • Smoking history;

  • Onset before the age of 50 years;

  • Infrapopliteal arterial occlusions;

  • Either arm involvement or phlebitis migrans;

  • Absence of atherosclerotic risk factors other than smoking.

Diagnostic Criteria of Olin

  • Age younger than 45 years

  • Current or recent history of tobacco use

  • Presence of distal extremity ischemia indicated by claudication, pain at rest, ischemic ulcers or gangrenes, and documented by non-invasive vascular testing;

  • Exclusion of autoimmune diseases, hypercoagulable states and diabetes mellitus;

  • Exclusion of a proximal source of embolization by echocardiography and arteriography;

  • Consistent arteriographic findings in the clinically involved and noninvolved limbs


Related Criteria

NYHA Functional Classification for Congestive Heart Failure

Framingham Criteria for Congestive Heart Failure

Cardiovascular Major Risk Factors

Duke Criteria for Infective Endocarditis (IE)

Revised Jones Criteria for Acute Rheumatic Fever (ARF)

Wells Clinical Prediction Rule for Pulmonary Embolism and Deep Venous Thrombosis

Braunwald Classification of Unstable Angina (UA)




  1. Olin JW. Thromboangiitis obliterans (Buerger's disease). N Engl J Med. 2000 Sep 21;343(12):864-9. [Medline]

  2. Shionoya S. Diagnostic criteria of Buerger's disease. Int J Cardiol. 1998 Oct 1;66 Suppl 1:S243-5. [Medline]

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Created: June 12, 2006
Last Modified: 10/17/2010

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