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TIMI Risk Score for ST-Elevation Myocardial Infarction (STEMI)

The TIMI risk score, based upon data from 15,000 patients with an ST segment elevation myocardial infarction eligible for fibrinolytic therapy, is a simple arithmetic sum of eight independent predictors of mortality.

TIMI Risk Score for STEMI


   Age 65-74

        >/= 75

2 points

3 points

   DM/HTN or Angina

1 point


   SBP < 100

3 points

   HR > 100

2 points

   Killip II-IV

2 points

   Weight < 67 kg

1 point


   Anterior STE or LBBB

1 point

   Time to rx > 4 hrs

1 point

   Risk Score = Total


DM, diabetes mellitus; HTN, hypertension; SBP, systolic blood pressure; HR, heart rate; STE, ST elevation; LBBB, left bundle branch block; and rx, treatment.

Risk Score

Odds of death by 30D*


0.1 (0.1-0.2)


0.3 (0.2-0.3)


0.4 (0.3-0.5)


0.7 (0.6-0.9)


1.2 (1.0-1.5)


2.2 (1.9-2.6)


3.0 (2.5-3.6)


4.8 (3.8-6.1)


5.8 (4.2-7.8)


8.8 (6.3-12)

* referenced to average mortality (95% confidence intervals)


Related Criteria

NYHA Functional Classification for Congestive Heart Failure

Framingham Criteria for Congestive Heart Failure

Cardiovascular Major Risk Factors

Duke Criteria for Infective Endocarditis (IE)

Revised Jones Criteria for Acute Rheumatic Fever (ARF)

Wells Clinical Prediction Rule for Pulmonary Embolism and Deep Venous Thrombosis

Braunwald Classification of Unstable Angina (UA)




  1. Morrow DA, Antman EM, Charlesworth A, Cairns R, Murphy SA, de Lemos JA, Giugliano RP, McCabe CH, Braunwald E. TIMI risk score for ST-elevation myocardial infarction: A convenient, bedside, clinical score for risk assessment at presentation: An intravenous nPA for treatment of infarcting myocardium early II trial substudy. Circulation. 2000 Oct 24;102(17):2031-7. [Medline]

  2. Morrow DA, Antman EM, Parsons L, de Lemos JA, Cannon CP, Giugliano RP, McCabe CH, Barron HV, Braunwald E. Application of the TIMI risk score for ST-elevation MI in the National Registry of Myocardial Infarction 3. JAMA. 2001 Sep 19;286(11):1356-9. [Medline]

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Created: Feb 18, 2007
Last Modified: 10/17/2010

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