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Harrison's Principles of Internal Medicine - 19th Edition (April 17, 2015)

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Alvarado Score for Acute Appendicitis Print E-mail
Written by G. Firman MD   
Thursday, 14 May 2015 03:29


The use of the Alvarado scoring system, which includes clinical examination findings and laboratory values, is helpful in ruling out appendicitis. Scores range from 1 to 10, with higher scores indicating a greater risk of appendicitis. When the score is less than 4, appendicitis is uncommon, and imaging and other interventions can be avoided.

Last Updated on Monday, 18 May 2015 07:57
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Tumor Markers in Clinical Practice Print E-mail
Written by G. Firman MD   
Wednesday, 11 March 2015 04:41


Tumor markers are playing an increasingly important role in cancer detection and management. These laboratory-based tests are potentially useful in screening for early malignancy, aiding cancer diagnosis, determining prognosis, surveillance following curative surgery for cancer, up front predicting drug response or resistance, and monitoring therapy in advanced disease.

Last Updated on Wednesday, 13 May 2015 06:43
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Guidelines for the Diagnosis of Prolonged Grief Disorder Print E-mail
Written by G. Firman MD   
Monday, 02 March 2015 07:32

 

 

The death of a loved one is one of life's greatest, universal stressors to which most bereaved individuals successfully adapt without clinical intervention. For a minority of bereaved individuals, grief is complicated by superimposed problems and healing does not occur. The resulting syndrome of complicated grief causes substantial distress and functional impairment even years after a loss, yet knowing when and how to intervene can be a challenge.

Last Updated on Friday, 27 March 2015 08:03
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Diagnostic Criteria for Multiple-System Atrophy (MSA) Print E-mail
Written by G. Firman MD   
Monday, 02 March 2015 07:36

 

Multiple system atrophy (MSA) is a sporadic and fatal alpha-synuclein-linked oligodendrogliopathy manifesting with progressive autonomic failure, poorly levodopa-responsive parkinsonism, and cerebellar ataxia, in any combination.

Last Updated on Saturday, 02 May 2015 06:25
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Diagnosis of Autoreactive Pericarditis Print E-mail
Written by G. Firman MD   
Thursday, 26 February 2015 04:50

 

Recently, the term "autoreactive pericarditis" has been introduced to describe patients with identification of elements indicative of an autoimmune response who would otherwise be classed as idiopathic.

Last Updated on Tuesday, 17 March 2015 04:11
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