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Severity Criteria for Clostridium difficile Infection Print E-mail
Written by G. Firman MD   
Friday, 06 January 2017 07:42
Patients with severe disease may develop a colonic ileus or toxic dilatation and present with abdominal pain and distension but with minimal or no diarrhea. Complications of severe C. difficile colitis include dehydration, electrolyte disturbances, hypoalbuminemia, toxic megacolon, bowel perforation, hypotension, renal failure, systemic inflammatory response syndrome, sepsis, and death.
Last Updated on Wednesday, 11 January 2017 05:19
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Definitions of Clostridium difficile Infection (CDI) Print E-mail
Written by G. Firman MD   
Thursday, 29 December 2016 07:02


Clostridium difficile ( C. difficile ) is a Gram-positive, sporeforming bacterium usually spread by the fecal-oral route. It is non-invasive and produces toxins A and B that cause disease, ranging from asymptomatic carriage, to mild diarrhea, to colitis, or pseudomembranous colitis. CDI is defined as the acute onset of diarrhea with documented toxigenic C. difficile or its toxin and no other documented cause for diarrhea. 

Last Updated on Thursday, 05 January 2017 06:07
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Interpretation of Dengue Diagnostic Tests Print E-mail
Written by G. Firman MD   
Thursday, 22 September 2016 05:54


Dengue virus infection produces a broad spectrum of symptoms, many of which are non-specific. Thus, a diagnosis based only on clinical symptoms is unreliable. Early laboratory confirmation of clinical diagnosis may be valuable because some patients progress over a short period from mild to severe disease and sometimes to death. Early intervention may be life-saving. 

Last Updated on Friday, 30 September 2016 07:11
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NYHA and Modified Ross Heart Failure Classification for Children Print E-mail
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Written by G. Firman MD   
Wednesday, 21 December 2016 04:37


The Ross Heart Failure Classification was developed to provide a global assessment of heart failure severity in infants, and has subsequently been modified to apply to all pediatric ages. The modified Ross Classification incorporates feeding difficulties, growth problems, and symptoms of exercise intolerance into a numeric score comparable with the NYHA classification for adults.

Last Updated on Wednesday, 21 December 2016 07:15
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Criteria for Testing for Diabetes or Prediabetes in Asymptomatic Adults Print E-mail
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Written by G. Firman MD   
Friday, 02 September 2016 06:38


“Prediabetes” is the term used for individuals with impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT) and indicates an increased risk for the future development of diabetes. IFG and IGT should not be viewed as clinical entities in their own right but rather risk factors for diabetes and cardiovascular disease (CVD). IFG and IGT are associated with obesity (especially abdominal or visceral obesity), dyslipidemia with high triglycerides and/or low HDL cholesterol, and hypertension.

Last Updated on Monday, 05 September 2016 06:33
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