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Diagnostic Criteria of Latent Autoimmune Diabetes in Adults (LADA) Print E-mail
Written by G. Firman MD   
Thursday, 26 January 2017 04:19


Latent autoimmune diabetes in adults (LADA) accounts for 2%-12% of all cases of diabetes. Patients are typically diagnosed after 35 years of age and are often misdiagnosed as type II Diabetes Mellitus (DM). Glycemic control is initially achieved with sulfonylureas but patients eventually become insulin dependent more rapidly than with type II DM patients. 

Last Updated on Friday, 27 January 2017 06:09
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Severity Criteria for Clostridium difficile Infection Print E-mail
Written by G. Firman MD   
Friday, 06 January 2017 07:42
Patients with severe disease may develop a colonic ileus or toxic dilatation and present with abdominal pain and distension but with minimal or no diarrhea. Complications of severe C. difficile colitis include dehydration, electrolyte disturbances, hypoalbuminemia, toxic megacolon, bowel perforation, hypotension, renal failure, systemic inflammatory response syndrome, sepsis, and death.
Last Updated on Wednesday, 11 January 2017 05:19
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NYHA and Modified Ross Heart Failure Classification for Children Print E-mail
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Written by G. Firman MD   
Wednesday, 21 December 2016 04:37


The Ross Heart Failure Classification was developed to provide a global assessment of heart failure severity in infants, and has subsequently been modified to apply to all pediatric ages. The modified Ross Classification incorporates feeding difficulties, growth problems, and symptoms of exercise intolerance into a numeric score comparable with the NYHA classification for adults.

Last Updated on Wednesday, 21 December 2016 07:15
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Definitions of Clostridium difficile Infection (CDI) Print E-mail
Written by G. Firman MD   
Thursday, 29 December 2016 07:02


Clostridium difficile ( C. difficile ) is a Gram-positive, sporeforming bacterium usually spread by the fecal-oral route. It is non-invasive and produces toxins A and B that cause disease, ranging from asymptomatic carriage, to mild diarrhea, to colitis, or pseudomembranous colitis. CDI is defined as the acute onset of diarrhea with documented toxigenic C. difficile or its toxin and no other documented cause for diarrhea. 

Last Updated on Thursday, 05 January 2017 06:07
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Interpretation of Dengue Diagnostic Tests Print E-mail
Written by G. Firman MD   
Thursday, 22 September 2016 05:54


Dengue virus infection produces a broad spectrum of symptoms, many of which are non-specific. Thus, a diagnosis based only on clinical symptoms is unreliable. Early laboratory confirmation of clinical diagnosis may be valuable because some patients progress over a short period from mild to severe disease and sometimes to death. Early intervention may be life-saving. 

Last Updated on Friday, 30 September 2016 07:11
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