|Diagnostic Criteria of Primary Sclerosing Cholangitis (PSC)|
|Written by G. Firman MD|
|Thursday, 12 January 2017 07:31|
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown cause that is characterized pathologically by an inflammatory and fibrotic process centered on the epithelium, leading to diffuse biliary stenosis and increased wall thickness throughout the intra- and extra-hepatic biliary trees.
Diagnostic Criteria of Primary Sclerosing Cholangitis (PSC)
It is necessary to exclude IgG4-related sclerosing cholangitis, secondary sclerosing cholangitis caused by diseases with an obvious pathogenesis, and malignant diseases such as biliary cancer.
A. Diagnostic items
I. Major items
A. Biliary tract imaging
1) Cholangiographic findings characteristic of PSC
2) Cholangiographic findings not specific to PSC
B. An increased alkaline phosphatase level
II. Minor items
a. Association with inflammatory bowel disease
b. Liver histology: Fibrous cholangitis/onion skin lesion
Lists of secondary sclerosing cholangitis
Created Jan 12, 2017.
Older news items:
|Last Updated on Wednesday, 01 March 2017 07:34|
Site Last Modified