English (United Kingdom)Español (spanish formal Internacional)

MC Facebook


Home Criteria Gastroenterology Typical Laboratory Abnormalities in Alcoholic Liver Disease (ALD)


The content of this website is provided for general informational purposes only and is not a substitute professional medical advice

Typical Laboratory Abnormalities in Alcoholic Liver Disease (ALD) Print E-mail
User Rating: / 3
Written by G. Firman MD   
Tuesday, 10 September 2013 06:52


Alcoholic liver disease (ALD) encompasses a spectrum of injury, ranging from simple steatosis to frank cirrhosis.


Typical Laboratory Abnormalities in ALD

Serum enzymes

  • AST >>> ALT: Both usually <300 IU/L
  • Alkaline phosphatase (ALP) and g-glutamyl transpeptidase (GGT): Both usually elevated to a variable degree

Metabolic alterations

  • Hyperglycemia
  • Hypertrygleridemia
  • Hyperuricemia
  • Electrolyte abnormalities: low potassium, magnesium and phosphorus

Tests of liver function

  • Serum albumin, prothrombin time, and serum bilirubin usually normal until significant liver injury present

Hematological abnormalities

  • Mild anemia common (usually macrocytic)
  • Platelets (normal to markedly decreased)
  • Elevated white blood cell count: Leukemoid reactions associated with alcoholic hepatitis


Abbreviations: AST, aspartate aminotransferase;  ALT, alanine aminotransferase



  1. O'Shea RS, Dasarathy S, McCullough AJ. Alcoholic liver disease. Am J Gastroenterol. 2010 Jan;105(1):14-32. [Medline]
  2. McCullough AJ, O'Connor JF. Alcoholic liver disease: proposed recommendations for the American College of Gastroenterology. Am J Gastroenterol. 1998 Nov;93(11):2022-36. [Medline]


Created Sep 10, 2013.


Related news items:
Newer news items:
Older news items:

Last Updated on Friday, 29 August 2014 17:19

Free Registry



HONcode accreditation seal. We comply with the HONcode standard for health trust worthy information:
verify here

Site Last Modified

Wednesday 17 January 2018, 14:29


Copyright © 2005-2018. All Rights Reserved