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Criteria for Grading Hepatic Encephalopathy Print E-mail


Grading of hepatic encephalopathy categorizes it in clinical stages of stepwise worsening. The description of each grade varies somewhat in the literature, but differences between adjacent grades are clear enough to be helpful in clinical practice, although neurologic descriptors are sparse. One study showed that for patients who become comatose, the Full Outline of Unresponsiveness (FOUR) score is more discriminating than the West Haven grading system because it includes brain-stem and respiration assessment, which are not further differentiated in the West Haven system.

Last Updated on Wednesday, 19 April 2017 05:04
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Wilson and Jungner Criteria for Screening Print E-mail


In 1968, Wilson and Jungner published 10 “principles” for evaluating screening programs, criteria widely used since then.

Last Updated on Thursday, 23 March 2017 06:46
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Diagnostic Criteria of Primary Sclerosing Cholangitis (PSC) Print E-mail


Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown cause that is characterized pathologically by an inflammatory and fibrotic process centered on the epithelium, leading to diffuse biliary stenosis and increased wall thickness throughout the intra- and extra-hepatic biliary trees.

Last Updated on Wednesday, 01 March 2017 07:34
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Severity Criteria for Clostridium difficile Infection Print E-mail
Patients with severe disease may develop a colonic ileus or toxic dilatation and present with abdominal pain and distension but with minimal or no diarrhea. Complications of severe C. difficile colitis include dehydration, electrolyte disturbances, hypoalbuminemia, toxic megacolon, bowel perforation, hypotension, renal failure, systemic inflammatory response syndrome, sepsis, and death.
Last Updated on Wednesday, 11 January 2017 05:19
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Initial Screening for Hereditary Breast and Ovarian Cancer Syndrome Print E-mail


The initial screening for hereditary breast and ovarian cancer syndrome should include specific questions about the patient's personal and family history of breast and ovarian cancers, risk assessment, education, and counseling.

Last Updated on Wednesday, 22 March 2017 13:36
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Diagnostic Criteria of Latent Autoimmune Diabetes in Adults (LADA) Print E-mail
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Latent autoimmune diabetes in adults (LADA) accounts for 2%-12% of all cases of diabetes. Patients are typically diagnosed after 35 years of age and are often misdiagnosed as type II Diabetes Mellitus (DM). Glycemic control is initially achieved with sulfonylureas but patients eventually become insulin dependent more rapidly than with type II DM patients. 

Last Updated on Friday, 27 January 2017 06:09
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