Diagnostic Criteria for Adult Respiratory Distress Syndrome (ARDS)

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	Diagnostic Criteria for Adult Respiratory Distress Syndrome (ARDS) Acute Respiratory Distress Syndrome (ARDS) is a syndrome of inflammation and increased permeability associated with a constellation of clinical, radiologic, and physiologic abnormalities unexplained by elevations in left atrial or pulmonary capillary pressure. All definitions of this syndrome include patients who meet the following criteria: Identifiable associated condition Acute onset Pulmonary artery wedge pressure </=18 mm Hg or absence of clinical evidence of left atrial hypertension Bilateral infiltrates on chest radiography Acute lung injury (ALI) is present if Pao₂/Fio₂ ratio is </= 300 Acute respiratory distress syndrome is present if Pao₂/Fio₂ ratio </= 200 ARDS = acute respiratory distress syndrome; Pao₂ = partial pressure of arterial oxygen; Fio₂ = percentage of inspired oxygen. Clinical Conditions Associated with Development of Acute Respiratory Distress Syndrome Direct lung injury Pneumonia Aspiration of gastric contents Inhalation injury Near drowning Pulmonary contusion Fat embolism Reperfusion pulmonary edema post lung transplantation or pulmonary embolectomy Indirect lung injury Sepsis Severe trauma Acute pancreatitis Cardiopulmonary bypass Massive transfusions Drug overdose Related Criteria Diagnostic Criteria for Sepsis Definitions for the Terms Bacteremia, Sepsis, Severe Sepsis, Septic Shock, and Other Related Disorders Diagnostic Criteria for Disseminated Intravascular Coagulation (DIC) More... References: Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L, Lamy M, Legall JR, Morris A, Spragg R. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med. 1994 Mar;149(3 Pt 1):818-24. [Medline] Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med. 2000 May 4;342(18):1334-49. [Medline] Mortelliti MP, Manning HL. Acute respiratory distress syndrome. Am Fam Physician. 2002 May 1;65(9):1823-30. [Medline] Sponsored Links				Principles of Critical Care, Third Edition, by J. Hall 3th edition (June 24, 2005) Textbook Of Critical Care, Fifth Edition, by M. Fink 5th Bk&Cdr edition (January 10, 2005)
	Created: April 24, 2005 Last Modified: 01/30/2007