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ROME II Diagnostic Criteria for Functional Esophageal Disorders

The diagnosis of a Functional Esophageal Disorder always presumes the absence of a structural or biochemical explanation for the symptoms.

A1. Globus

At least 12 weeks, which need not be consecutive, in the preceding 12 months of:

1. The persistent or intermittent sensation of a lump or foreign body in the throat;

2. Occurrence of the sensation between meals;

3. Absence of dysphagia and odynophagia; and

4. Absence of pathologic gastroesophageal reflux, achalasia, or other motility disorder with a recognized pathologic basis (e.g., scleroderma of the esophagus).

A2. Rumination Syndrome

At least 12 weeks, which need not be consecutive, in the preceding 12 months of:

1. Persistent or recurrent regurgitation of recently ingested food into the mouth with subsequent remastication and swallowing or spitting it out;

2. Absence of nausea and vomiting;

3. Cessation of the process when the regurgitated material becomes acidic; and

4. Absence of pathologic gastroesophageal reflux, achalasia, or other motility disorder with a recognized pathologic basis as the primary disorder.

A3. Functional Chest Pain of Presumed Esophageal Origin

At least 12 weeks, which need not be consecutive, within the preceding 12 months of:

1. Midline chest pain or discomfort that is not of burning quality; and

2. Absence of pathologic gastroesophageal reflux, achalasia, or other motility disorder with a recognized pathologic basis.

A4. Functional Heartburn

At least 12 weeks, which need not be consecutive, in the preceding 12 months of:

1. Burning retrosternal discomfort or pain; and

2. Absence of pathologic gastroesophageal reflux, achalasia, or other motility disorder with a recognized pathologic basis.

A5. Functional Dysphagia

At least 12 weeks, which need not be consecutive, in the preceding 12 months of:

1. Sense of solid and/or liquid foods sticking, lodging, or passing abnormally through the esophagus; and

2. Absence of pathologic gastroesophageal reflux, achalasia, or other motility disorder with a recognized pathologic basis.

A6. Unspecified Functional Esophageal Disorder

At least 12 weeks, which need not be consecutive, in the preceding 12 months of:

1. Unexplained symptoms attributed to the esophagus that do not fit into the previously described categories; and

2. Absence of pathologic gastroesophageal reflux, achalasia, or other motility disorder with a recognized pathologic basis.

Related Criteria

ROME II Diagnostic Criteria for Functional Gastroduodenal Disorders

ROME II Diagnostic Criteria for Functional Bowel Disorders

ROME II Diagnostic Criteria for Functional Abdominal Pain

ROME II Diagnostic Criteria for Functional Disorders of the Biliary Tract and the Pancreas

ROME II Diagnostic Criteria for Functional Disorders of the Anus and Rectum

ROME II Diagnostic Criteria for Childhood Functional Gastrointestinal Disorders

More...

References:

1. Douglas A. Drossman. ROME II: The Functional Gastrointestinal Disorders, Second Edition

This material was taken from the ROME II. It is intended for educational purposes only.

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Created: March 19, 2005
Last Modified: 12/24/2006

Rome II: The Functional Gastrointestinal Disorders
by Douglas A. Drossman (Hardcover)

Handbook of Functional Gastrointestinal Disorders
by Kevin W. Olden

Rome II: The Functional Gastrointestinal Disorders
by Douglas A. Drossman (Paperback)