Diagnosis and
Indications for Treatment of
Molluscum Contagiosum
Molluscum
contagiosum is generally a
benign disease consisting of
pearly, flesh-colored,
umbilicated skin lesions 2 to 5
mm in diameter with a
characteristic dimple at the
center
The diagnosis
of molluscum contagiosum is
usually made by the
characteristic appearance of the
lesions. When necessary,
histologic or electron
microscopic (EM) examination can
confirm the clinical diagnosis.
Hematoxylin and eosin staining
reveals keratinocytes containing
eosinophilic cytoplasmic
inclusion bodies. EM of such
biopsies would reveal typical
brick-shaped poxvirus particles,
similar to those of smallpox. EM
also shows some infected cells
that might look normal using
light microscopy.
Reasons to
treat molluscum contagiosum
include:
-
alleviating
discomfort, including itching;
-
cosmetic
reasons;
-
social
stigma associated with many
visible lesions;
-
limiting
it’s spread to other areas of
the body and to other people;
-
preventing
scarring and secondary
infection;
-
preventing
trauma and bleeding of
lesions.
References:
-
van der Wouden
JC, Menke J,
Gajadin S,
Koning S,
Tasche MJ, van
Suijlekom-Smit
LW, Berger MY,
Butler CC.
Interventions
for cutaneous
molluscum
contagiosum.
Cochrane
Database Syst
Rev. 2006 Apr
19;(2):CD004767.
[Medline]
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