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International Clinical Diabetic
Retinopathy and Diabetic Macular
Edema Disease Severity Scales
|
International Clinical
Diabetic Retinopathy Disease
Severity Scale |
|
Proposed Disease Severity
Level |
Findings
Observable upon Dilated
Ophthalmoscopy |
|
No
apparent retinopathy |
No
abnormalities |
|
Mild
nonproliferative diabetic
retinopathy |
Microaneurysms only |
|
Moderate nonproliferative
diabetic retinopathy |
More than
just microaneurysms but less
than severe NPDR |
|
Severe
nonproliferative diabetic
retinopathy |
Any of
the following:
More than
20 intraretinal hemorrhages
in each of four quadrants
Definite
venous beading in two or
more quadrants
Prominent
IRMA in one or more
quadrants
And no
signs of proliferative
retinopathy |
|
Proliferative diabetic
retinopathy |
One or
both of the following:
Neovascularization
Vitreous/preretinal
hemorrhage |
IRMA =
intraretinal microvascular
abnormalities; NPDR =
nonproliferative diabetic
retinopathy
|
International Clinical
Diabetic Macular Edema
Disease Severity Scale |
|
Proposed Disease Severity
Level |
Findings
Observable upon Dilated
Ophthalmoscopy |
|
Diabetic
macular edema apparently
absent
Diabetic
macular edema apparently
present |
No
apparent retinal thickening
or hard exudates in
posterior pole
Some
apparent retinal thickening
or hard exudates in
posterior pole |
|
If
diabetic macular edema is
present, it can be
categorized as follows: |
|
Proposed Disease Severity
Level |
Findings
Observable upon Dilated
Ophthalmoscopy* |
|
Diabetic macular edema
present . |
Mild
diabetic macular edema: Some
retinal thickening or hard
exudates in posterior pole
but distant from the center
of the macula |
|
Moderate
diabetic macular edema:
Retinal thickening or hard
exudates approaching the
center of the macula but not
involving the center |
|
Severe
diabetic macular edema:
Retinal thickening or hard
exudates involving the
center of the macula . . |
* Hard
exudates are a sign of current
or previous macular edema.
Diabetic macular edema is
defined as retinal thickening;
this requires a
three-dimensional assessment
that is best performed by
dilated examination using
slit-lamp biomicroscopy and/or
stereo fundus photography.
Related Criteria
Criteria for the Diagnosis of Diabetes Mellitus
More...
References:
-
Wilkinson CP,
Ferris FL 3rd,
Klein RE, Lee PP,
Agardh CD, Davis
M, Dills D, Kampik
A, Pararajasegaram
R, Verdaguer JT;
Global Diabetic
Retinopathy
Project Group.
Proposed
international
clinical diabetic
retinopathy and
diabetic macular
edema disease
severity scales.
Ophthalmology.
2003
Sep;110(9):1677-82.
[Medline]
-
Ciulla TA, Amador
AG, Zinman B.
Diabetic
retinopathy and
diabetic macular
edema:
pathophysiology,
screening, and
novel therapies.
Diabetes Care.
2003
Sep;26(9):2653-64.
[Medline]
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Created: September 12, 2006 Last Modified:
10/17/2010
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